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TIGIT in cancer immunotherapy

Tumors evade immune-mediated recognition through multiple mechanisms of immune escape. On chronic tumor antigen exposure, T cells become dysfunctional/exhausted and upregulate various checkpoint inhibitory receptors (IRs) that limit T cells’ survival and function. During the last decade, immunothera...

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Detalles Bibliográficos
Autores principales: Chauvin, Joe-Marc, Zarour, Hassane M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477968/
https://www.ncbi.nlm.nih.gov/pubmed/32900861
http://dx.doi.org/10.1136/jitc-2020-000957