Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources

BACKGROUND: Adoptive cell therapy with chimeric antigen receptor T cells (CAR-T) has become a standard treatment for patients with certain aggressive B cell malignancies and holds promise to improve the care of patients suffering from numerous other cancers in the future. However, the high manufactu...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidts, Andrea, Marsh, Leah C, Srivastava, Ambike A, Bouffard, Amanda A, Boroughs, Angela C, Scarfò, Irene, Larson, Rebecca C, Bedoya, Felipe, Choi, Bryan D, Frigault, Matthew J, Bailey, Stefanie R, Leick, Mark B, Vatsa, Sonika, Kann, Michael C, Prew, Michelle S, Kleinstiver, Benjamin P, Joung, J Keith, Maus, Marcela V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477986/
https://www.ncbi.nlm.nih.gov/pubmed/32900862
http://dx.doi.org/10.1136/jitc-2020-000990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477986/
https://www.ncbi.nlm.nih.gov/pubmed/32900862
http://dx.doi.org/10.1136/jitc-2020-000990

Ejemplares similares