MKL1 Mediates TGF-β Induced RhoJ Transcription to Promote Breast Cancer Cell Migration and Invasion

Differential regulation of gene transcription contributes to cancer metastasis. We investigated the involvement of a Rho GTPase (RhoJ) in breast cancer metastasis focusing on the mechanism underlying RhoJ trans-activation by pro-metastatic cues. We report that expression of RhoJ was up-regulated in...

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Detalles Bibliográficos
Autores principales: Chen, Baoyu, Yuan, Yibiao, Sun, Lina, Chen, Junliang, Yang, Mengzhu, Yin, Yongmei, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478007/
https://www.ncbi.nlm.nih.gov/pubmed/32984327
http://dx.doi.org/10.3389/fcell.2020.00832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478007/
https://www.ncbi.nlm.nih.gov/pubmed/32984327
http://dx.doi.org/10.3389/fcell.2020.00832

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