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Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes

INTRODUCTION: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease worldwide. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway participates in the development and progression of DN. Among the different mechanisms involved in JAK/STAT negative...

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Detalles Bibliográficos
Autores principales: Opazo-Ríos, Lucas, Sanchez Matus, Yenniffer, Rodrigues-Díez, Raúl R, Carpio, Daniel, Droguett, Alejandra, Egido, Jesús, Gomez-Guerrero, Carmen, Mezzano, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478022/
https://www.ncbi.nlm.nih.gov/pubmed/32900697
http://dx.doi.org/10.1136/bmjdrc-2020-001242