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A rapid HPLC–DAD method for quantification of amikacin in pharmaceuticals and biological samples using pre-column derivatization with Hantzsch reagent

Amikacin (AMK) is an important member of aminoglycoside class, and its determination has therapeutic importance due to its matchless potency against gram –ve pathogens. Due to narrow therapeutic window, its monitoring in clinical samples is inevitable. Direct determination of AMK using HPLC with UV–...

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Detalles Bibliográficos
Autores principales: Maheshwari, Madan Lal, Memon, Najma, Memon, Ayaz Ali, Khuhawar, Muhammad Yar, Memon, Abdul Hakeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478114/
http://dx.doi.org/10.1007/s13738-020-02046-2