AKT-mediated phosphorylation of TWIST1 is essential for breast cancer cell metastasis

Previously, it was shown that human TWIST1 (basic helix-loop-helix (b-HLH) is phosphorylated by Akt kinase at S42, T121, and S123. To show in vivo effect of these phosphorylations, we created mouse TWIST1 expression vector and converted the codons of S42, T125, and S127 to unphosphorylatable alanine...

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Detalles Bibliográficos
Autores principales: ERTOSUN, Mustafa Gökhan, PEHLİVANOĞLU, Suray, DİLMAÇ, Sayra, TANRIÖVER, Gamze, ÖZEŞ, Osman Nidai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478131/
https://www.ncbi.nlm.nih.gov/pubmed/32922123
http://dx.doi.org/10.3906/biy-1912-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478131/
https://www.ncbi.nlm.nih.gov/pubmed/32922123
http://dx.doi.org/10.3906/biy-1912-74

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