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AKT-mediated phosphorylation of TWIST1 is essential for breast cancer cell metastasis
Previously, it was shown that human TWIST1 (basic helix-loop-helix (b-HLH) is phosphorylated by Akt kinase at S42, T121, and S123. To show in vivo effect of these phosphorylations, we created mouse TWIST1 expression vector and converted the codons of S42, T125, and S127 to unphosphorylatable alanine...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Scientific and Technological Research Council of Turkey
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478131/ https://www.ncbi.nlm.nih.gov/pubmed/32922123 http://dx.doi.org/10.3906/biy-1912-74 |