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Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations

Regulation of NK cell activity is mediated through killer-cell immunoglobulin-like receptors (KIR) ability to recognize human leukocyte antigen (HLA) class I molecules as ligands. Interaction of KIR and HLA is implicated in viral infections, autoimmunity, and reproduction and there is growing eviden...

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Detalles Bibliográficos
Autores principales: Vargas, Luciana de Brito, Dourado, Renata M., Amorim, Leonardo M., Ho, Brenda, Calonga-Solís, Verónica, Issler, Hellen C., Marin, Wesley M., Beltrame, Marcia H., Petzl-Erler, Maria Luiza, Hollenbach, Jill A., Augusto, Danillo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478174/
https://www.ncbi.nlm.nih.gov/pubmed/32983108
http://dx.doi.org/10.3389/fimmu.2020.01881