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Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons

BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to meld these observations into a unified model for axona...

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Detalles Bibliográficos
Autores principales: De Pace, Raffaella, Britt, Dylan J., Mercurio, Jeffrey, Foster, Arianne M., Djavaherian, Lucas, Hoffmann, Victoria, Abebe, Daniel, Bonifacino, Juan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478246/
https://www.ncbi.nlm.nih.gov/pubmed/32553155
http://dx.doi.org/10.1016/j.celrep.2020.107775