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Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons
BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to meld these observations into a unified model for axona...
Autores principales: | De Pace, Raffaella, Britt, Dylan J., Mercurio, Jeffrey, Foster, Arianne M., Djavaherian, Lucas, Hoffmann, Victoria, Abebe, Daniel, Bonifacino, Juan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478246/ https://www.ncbi.nlm.nih.gov/pubmed/32553155 http://dx.doi.org/10.1016/j.celrep.2020.107775 |
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