Cargando…

Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons

BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to meld these observations into a unified model for axona...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Pace, Raffaella, Britt, Dylan J., Mercurio, Jeffrey, Foster, Arianne M., Djavaherian, Lucas, Hoffmann, Victoria, Abebe, Daniel, Bonifacino, Juan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478246/ https://www.ncbi.nlm.nih.gov/pubmed/32553155 http://dx.doi.org/10.1016/j.celrep.2020.107775

Ejemplares similares

Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons
por: Watson, Emma T, et al.
Publicado: (2023)

Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome
por: De Pace, Raffaella, et al.
Publicado: (2018)

Optogenetic Acidification of Synaptic Vesicles and Lysosomes
por: Rost, Benjamin R., et al.
Publicado: (2015)

Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning
por: Vitet, Hélène, et al.
Publicado: (2023)

Axonal Synapses Utilize Multiple Synaptic Ribbons in the Mammalian Retina
por: Kim, Hong-Lim, et al.
Publicado: (2012)

Hidden proteome of synaptic vesicles in the mammalian brain
por: Taoufiq, Zacharie, et al.
Publicado: (2020)

Fast axonal transport of foreign synaptic vesicles in squid axoplasm
Publicado: (1985)

Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling
por: Granseth, Björn, et al.
Publicado: (2013)

Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles
por: Groemer, Teja W., et al.
Publicado: (2011)

Lysosomal enzyme precursors in coated vesicles derived from the exocytic and endocytic pathways
Publicado: (1987)

Visualization of the Dynamics of Synaptic Vesicle and Plasma Membrane Proteins in Living Axons
por: Nakata, Takao, et al.
Publicado: (1998)

Protocol for Quantitative Analysis of Synaptic Vesicle Clustering in Axons of Cultured Neurons
por: Um, Ji Won, et al.
Publicado: (2020)

ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability
por: Özkan, Nazmiye, et al.
Publicado: (2021)

AXONAL AGRANULAR RETICULUM AND SYNAPTIC VESICLES IN CULTURED EMBRYONIC CHICK SYMPATHETIC NEURONS
por: Teichberg, Saul, et al.
Publicado: (1973)

Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth
por: Almeida, Rafael G., et al.
Publicado: (2021)

Axonal transport of Hrs is activity dependent and facilitates synaptic vesicle protein degradation
por: Birdsall, Veronica, et al.
Publicado: (2022)

Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain
por: Chantranupong, Lynne, et al.
Publicado: (2020)

De novo mutations in KIF1A-associated neuronal disorder (KAND) dominant-negatively inhibit motor activity and axonal transport of synaptic vesicle precursors
por: Anazawa, Yuzu, et al.
Publicado: (2022)

The mammalian rod synaptic ribbon is essential for Ca(v) channel facilitation and ultrafast synaptic vesicle fusion
por: Grabner, Chad Paul, et al.
Publicado: (2021)

Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3
por: Ahmad, Tanveer, et al.
Publicado: (2022)

Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin
por: Courtney, Nicholas A., et al.
Publicado: (2019)

Rapid isolation and cryo‐EM characterization of synaptic vesicles from mammalian brain
por: Du, Kang, et al.
Publicado: (2022)

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors
por: Dou, Dan, et al.
Publicado: (2023)

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
por: Sanchez-Varo, Raquel, et al.
Publicado: (2011)

Circulation and turnover of synaptic vesicle membrane in cultured fetal mammalian spinal cord neurons
Publicado: (1975)

Distinguishing synaptic vesicle precursor navigation of microtubule ends with a single rate constant model
por: Gramlich, M. W., et al.
Publicado: (2021)

Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration
por: Fernandes, Ana Clara, et al.
Publicado: (2014)

Axon's vesicles in excess
por: LeBrasseur, Nicole
Publicado: (2006)

A cryo-ET survey of microtubules and intracellular compartments in mammalian axons
por: Foster, Helen E., et al.
Publicado: (2021)

The adaptor protein chaperone AAGAB stabilizes AP-4 complex subunits
por: Mattera, Rafael, et al.
Publicado: (2022)

Synaptic Function and Dysfunction in Lysosomal Storage Diseases
por: Rebiai, Rima, et al.
Publicado: (2021)

Lysosomal Function and Axon Guidance: Is There a Meaningful Liaison?
por: Manzoli, Rosa, et al.
Publicado: (2021)

BORC coordinates encounter and fusion of lysosomes with autophagosomes
por: Jia, Rui, et al.
Publicado: (2017)

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus
por: Torres, Manuel, et al.
Publicado: (2012)

Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: differential effects of Brefeldin A in axon and dendrites
Publicado: (1993)

Targeting of the Synaptic Vesicle Protein Synaptobrevin in the Axon of Cultured Hippocampal Neurons: Evidence for Two Distinct Sorting Steps
por: West, Anne E., et al.
Publicado: (1997)

Study on the Dynamic Changes in Synaptic Vesicle-Associated Protein and Axonal Transport Protein Combined with LPS Neuroinflammation Model
por: Zhang, Rui, et al.
Publicado: (2013)

SYN2 is an autism predisposing gene: loss-of-function mutations alter synaptic vesicle cycling and axon outgrowth
por: Corradi, Anna, et al.
Publicado: (2014)

Mapping mammalian synaptic connectivity
por: Yook, Chaehyun, et al.
Publicado: (2013)

The discovery of synaptic vesicles
por: Wells, William A.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_e346l4miie855itag31f5sjc16