Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors

OBJECTIVE(S): Allylbenzenes have been recently developed as inhibitors of lipoxygenases. They decrease peroxidation activity via mimicking 1,4-unsaturated bonds of fatty acids by their allyl portion. We designed and synthesized new derivatives of allyl benzenes (6a-f) with isopropoxy and amide subst...

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Detalles Bibliográficos
Autores principales: Mousavian, Mina, Alavi, Seyed Jamal, Rahbarian, Raheleh, Rajabian, Majid, M. Orafai, Hossein, Sadeghian, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478253/
https://www.ncbi.nlm.nih.gov/pubmed/32952943
http://dx.doi.org/10.22038/ijbms.2020.36793.8763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478253/
https://www.ncbi.nlm.nih.gov/pubmed/32952943
http://dx.doi.org/10.22038/ijbms.2020.36793.8763

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