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Bioinformatics prediction and experimental validation of VH antibody fragment interacting with Neisseria meningitidis factor H binding protein

OBJECTIVE(S): We previously conducted an in silico research on the interactions between the ribosome display-selected single chain variable fragment (scFv) and factor H binding protein (fHbp) of Neisseria meningitidis. We found that heavy chain variable (VH) fragment of this scFv had considerable af...

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Detalles Bibliográficos
Autores principales: Rafighdoust, Hediyeh, Ahangarzadeh, Shahrzad, Yarian, Fatemeh, Taheri, Ramezan Ali, Lari, Arezou, Bandehpour, Mojgan, Salahshoor Dahr, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478258/
https://www.ncbi.nlm.nih.gov/pubmed/32952952
http://dx.doi.org/10.22038/ijbms.2020.44007.10318