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Evaluation of methods for detecting human reads in microbial sequencing datasets

Sequencing data from host-associated microbes can often be contaminated by the body of the investigator or research subject. Human DNA is typically removed from microbial reads either by subtractive alignment (dropping all reads that map to the human genome) or by using a read classification tool to...

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Detalles Bibliográficos
Autores principales: Bush, Stephen J., Connor, Thomas R., Peto, Tim E.A., Crook, Derrick W., Walker, A. Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478626/
https://www.ncbi.nlm.nih.gov/pubmed/32558637
http://dx.doi.org/10.1099/mgen.0.000393