Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

Tumor cells rely on glutamine to fulfill their metabolic demands and sustain proliferation. The elevated consumption of glutamine can lead to intratumoral nutrient depletion, causing metabolic stress that has the potential to impact tumor progression. Here, we show that nutrient stress caused by glu...

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Detalles Bibliográficos
Autores principales: Recouvreux, Maria Victoria, Moldenhauer, Matthew R., Galenkamp, Koen M.O., Jung, Michael, James, Brian, Zhang, Yijuan, Lowy, Andrew, Bagchi, Anindya, Commisso, Cosimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478719/
https://www.ncbi.nlm.nih.gov/pubmed/32510550
http://dx.doi.org/10.1084/jem.20200388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478719/
https://www.ncbi.nlm.nih.gov/pubmed/32510550
http://dx.doi.org/10.1084/jem.20200388

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