Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation

Cell differentiation is accompanied by epigenetic changes leading to precise lineage definition and cell identity. Here we present a comprehensive resource of epigenomic data of human T cell precursors along with an integrative analysis of other hematopoietic populations. Although T cell commitment...

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Detalles Bibliográficos
Autores principales: Cieslak, Agata, Charbonnier, Guillaume, Tesio, Melania, Mathieu, Eve-Lyne, Belhocine, Mohamed, Touzart, Aurore, Smith, Charlotte, Hypolite, Guillaume, Andrieu, Guillaume P., Martens, Joost H.A., Janssen-Megens, Eva, Gut, Marta, Gut, Ivo, Boissel, Nicolas, Petit, Arnaud, Puthier, Denis, Macintyre, Elizabeth, Stunnenberg, Hendrik G., Spicuglia, Salvatore, Asnafi, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478722/
https://www.ncbi.nlm.nih.gov/pubmed/32667968
http://dx.doi.org/10.1084/jem.20192360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478722/
https://www.ncbi.nlm.nih.gov/pubmed/32667968
http://dx.doi.org/10.1084/jem.20192360

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