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Japanese encephalitis virus–primed CD8(+) T cells prevent antibody-dependent enhancement of Zika virus pathogenesis

Cross-reactive anti-flaviviral immunity can influence the outcome of infections with heterologous flaviviruses. However, it is unclear how the interplay between cross-reactive antibodies and T cells tilts the balance toward pathogenesis versus protection during secondary Zika virus (ZIKV) and Japane...

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Detalles Bibliográficos
Autores principales: Chen, Dong, Duan, Zhiliang, Zhou, Wenhua, Zou, Weiwei, Jin, Shengwei, Li, Dezhou, Chen, Xinyu, Zhou, Yongchao, Yang, Lan, Zhang, Yanjun, Shresta, Sujan, Wen, Jinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478723/
https://www.ncbi.nlm.nih.gov/pubmed/32501510
http://dx.doi.org/10.1084/jem.20192152