BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression

Regulatory T (Treg) cell populations are composed of functionally quiescent resting Treg (rTreg) cells which differentiate into activated Treg (aTreg) cells upon antigen stimulation. How rTreg cells remain quiescent despite chronic exposure to cognate self- and foreign antigens is unclear. The trans...

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Detalles Bibliográficos
Autores principales: Grant, Francis M., Yang, Jie, Nasrallah, Rabab, Clarke, James, Sadiyah, Firas, Whiteside, Sarah K., Imianowski, Charlotte J., Kuo, Paula, Vardaka, Panagiota, Todorov, Tihomir, Zandhuis, Nordin, Patrascan, Ilinca, Tough, David F., Kometani, Kohei, Eil, Robert, Kurosaki, Tomohiro, Okkenhaug, Klaus, Roychoudhuri, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478731/
https://www.ncbi.nlm.nih.gov/pubmed/32515782
http://dx.doi.org/10.1084/jem.20190711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478731/
https://www.ncbi.nlm.nih.gov/pubmed/32515782
http://dx.doi.org/10.1084/jem.20190711

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