Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases

Chronic pain is a major comorbidity of chronic inflammatory diseases. Here, we report that the cytokine IL-1β, which is abundantly produced during multiple sclerosis (MS), arthritis (RA), and osteoarthritis (OA) both in humans and in animal models, drives pain associated with these diseases. We foun...

Descripción completa

Detalles Bibliográficos
Autores principales: Mailhot, Benoit, Christin, Marine, Tessandier, Nicolas, Sotoudeh, Chaudy, Bretheau, Floriane, Turmel, Roxanne, Pellerin, Ève, Wang, Feng, Bories, Cyril, Joly-Beauparlant, Charles, De Koninck, Yves, Droit, Arnaud, Cicchetti, Francesca, Scherrer, Grégory, Boilard, Eric, Sharif-Naeini, Reza, Lacroix, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478735/
https://www.ncbi.nlm.nih.gov/pubmed/32573694
http://dx.doi.org/10.1084/jem.20191430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478735/
https://www.ncbi.nlm.nih.gov/pubmed/32573694
http://dx.doi.org/10.1084/jem.20191430

Ejemplares similares