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Propofol induces mitochondrial-associated protein LRPPRC and protects mitochondria against hypoxia in cardiac cells
BACKGROUND: Hypoxia-induced oxidative stress is one of the main mechanisms of myocardial injury, which frequently results in cardiomyocyte death and precipitates life-threatening heart failure. Propofol (2,6-diisopropylphenol), which is used to sedate patients during surgery, was shown to strongly a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478836/ https://www.ncbi.nlm.nih.gov/pubmed/32898195 http://dx.doi.org/10.1371/journal.pone.0238857 |