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Propofol induces mitochondrial-associated protein LRPPRC and protects mitochondria against hypoxia in cardiac cells

BACKGROUND: Hypoxia-induced oxidative stress is one of the main mechanisms of myocardial injury, which frequently results in cardiomyocyte death and precipitates life-threatening heart failure. Propofol (2,6-diisopropylphenol), which is used to sedate patients during surgery, was shown to strongly a...

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Detalles Bibliográficos
Autores principales: Zhang, Qianlu, Cai, Shiwei, Guo, Liping, Zhao, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478836/
https://www.ncbi.nlm.nih.gov/pubmed/32898195
http://dx.doi.org/10.1371/journal.pone.0238857