Cargando…
Propofol induces mitochondrial-associated protein LRPPRC and protects mitochondria against hypoxia in cardiac cells
BACKGROUND: Hypoxia-induced oxidative stress is one of the main mechanisms of myocardial injury, which frequently results in cardiomyocyte death and precipitates life-threatening heart failure. Propofol (2,6-diisopropylphenol), which is used to sedate patients during surgery, was shown to strongly a...
Autores principales: | Zhang, Qianlu, Cai, Shiwei, Guo, Liping, Zhao, Guojun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478836/ https://www.ncbi.nlm.nih.gov/pubmed/32898195 http://dx.doi.org/10.1371/journal.pone.0238857 |
Ejemplares similares
-
SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation
por: Lagouge, Marie, et al.
Publicado: (2015) -
LRPPRC-mediated folding of the mitochondrial transcriptome
por: Siira, Stefan J., et al.
Publicado: (2017) -
The loss of LRPPRC function induces the mitochondrial unfolded protein response
por: Köhler, Fabian, et al.
Publicado: (2015) -
The Leucine-rich Pentatricopeptide Repeat-containing Protein (LRPPRC) Does Not Activate Transcription in Mammalian Mitochondria
por: Harmel, Julia, et al.
Publicado: (2013) -
Mitochondrial and Nuclear Genomic Responses to Loss of LRPPRC Expression
por: Gohil, Vishal M., et al.
Publicado: (2010)