Treatment estimands in clinical trials of patients hospitalised for COVID-19: ensuring trials ask the right questions

When designing a clinical trial, explicitly defining the treatment estimands of interest (that which is to be estimated) can help to clarify trial objectives and ensure the questions being addressed by the trial are clinically meaningful. There are several challenges when defining estimands. Here, w...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C., Morris, Tim P., White, Ian R., Tweed, Conor D., Cro, Suzie, Dahly, Darren, Pham, Tra My, Esmail, Hanif, Babiker, Abdel, Carpenter, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478913/
https://www.ncbi.nlm.nih.gov/pubmed/32900372
http://dx.doi.org/10.1186/s12916-020-01737-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478913/
https://www.ncbi.nlm.nih.gov/pubmed/32900372
http://dx.doi.org/10.1186/s12916-020-01737-0

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