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Treatment estimands in clinical trials of patients hospitalised for COVID-19: ensuring trials ask the right questions
When designing a clinical trial, explicitly defining the treatment estimands of interest (that which is to be estimated) can help to clarify trial objectives and ensure the questions being addressed by the trial are clinically meaningful. There are several challenges when defining estimands. Here, w...
Autores principales: | Kahan, Brennan C., Morris, Tim P., White, Ian R., Tweed, Conor D., Cro, Suzie, Dahly, Darren, Pham, Tra My, Esmail, Hanif, Babiker, Abdel, Carpenter, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478913/ https://www.ncbi.nlm.nih.gov/pubmed/32900372 http://dx.doi.org/10.1186/s12916-020-01737-0 |
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