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Evaluation of patient-reported severity of hand–foot syndrome under capecitabine using a Markov modeling approach

PURPOSE: The inclusion of the patient’s perspective has become increasingly important when reporting adverse events and may assist in management of toxicity. The relationship between drug exposure and toxicity can be quantified by combining Markov elements with pharmacometric models. A minimal conti...

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Detalles Bibliográficos
Autores principales: Schmulenson, Eduard, Krolop, Linda, Simons, Sven, Ringsdorf, Susanne, Ko, Yon-Dschun, Jaehde, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478943/
https://www.ncbi.nlm.nih.gov/pubmed/32852627
http://dx.doi.org/10.1007/s00280-020-04128-7