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Behavioral effects of SGK1 knockout in VTA and dopamine neurons

Drugs of abuse cause significant neuroadaptations within the ventral tegmental area (VTA), with alterations in gene expression tied to changes in reward behavior. Serum- and glucocorticoid-inducible kinase 1 (SGK1) transcription, catalytic activity, and phosphorylation are upregulated in the VTA by...

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Detalles Bibliográficos
Autores principales: Doyle, Marie A., Stark, Ali R., Fejes-Tóth, Geza, Náray-Fejes-Tóth, Aniko, Mazei-Robison, Michelle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478959/
https://www.ncbi.nlm.nih.gov/pubmed/32901079
http://dx.doi.org/10.1038/s41598-020-71681-9