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Behavioral effects of SGK1 knockout in VTA and dopamine neurons
Drugs of abuse cause significant neuroadaptations within the ventral tegmental area (VTA), with alterations in gene expression tied to changes in reward behavior. Serum- and glucocorticoid-inducible kinase 1 (SGK1) transcription, catalytic activity, and phosphorylation are upregulated in the VTA by...
Autores principales: | Doyle, Marie A., Stark, Ali R., Fejes-Tóth, Geza, Náray-Fejes-Tóth, Aniko, Mazei-Robison, Michelle S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478959/ https://www.ncbi.nlm.nih.gov/pubmed/32901079 http://dx.doi.org/10.1038/s41598-020-71681-9 |
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