Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis

Centromeres are epigenetically determined nuclear domains strictly required for chromosome segregation and genome stability. However, the mechanisms regulating centromere and kinetochore chromatin modifications are not known. Here, we demonstrate that LSH is enriched at meiotic kinetochores and its...

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Detalles Bibliográficos
Autores principales: Baumann, Claudia, Ma, Wei, Wang, Xiaotian, Kandasamy, Muthugapatti K., Viveiros, Maria M., De La Fuente, Rabindranath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478982/
https://www.ncbi.nlm.nih.gov/pubmed/32900989
http://dx.doi.org/10.1038/s41467-020-18009-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478982/
https://www.ncbi.nlm.nih.gov/pubmed/32900989
http://dx.doi.org/10.1038/s41467-020-18009-3

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