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miR-331-3p is involved in glucocorticoid resistance reversion by rapamycin through suppression of the MAPK signaling pathway

Glucocorticoids (GCs) are commonly used as therapeutic agents for immune-mediated diseases and leukemia. However, considerable inter-individual differences in efficacy have been reported. Several reports indicate that the inhibitor of mTOR rapamycin can reverse GC resistance, but the molecular mecha...

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Detalles Bibliográficos
Autores principales: Lucafò, Marianna, Sicari, Daria, Chicco, Andrea, Curci, Debora, Bellazzo, Arianna, Di Silvestre, Alessia, Pegolo, Chiara, Autry, Robert, Cecchin, Erika, De Iudicibus, Sara, Collavin, Licio, Evans, William, Decorti, Giuliana, Stocco, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479018/
https://www.ncbi.nlm.nih.gov/pubmed/32776229
http://dx.doi.org/10.1007/s00280-020-04122-z