Cargando…

CP49 and filensin intermediate filaments are essential for formation of cold cataract

PURPOSE: To investigate the molecular and cellular mechanisms of cataract induced by cold temperatures in young lenses of wild-type C57BL/6J (B6), wild-type 129SvJae (129), and filensin knockout (KO) mice. To determine how lens intermediate filament proteins, filensin (BFSP1) and CP49 (BFSP2), are i...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yuxing, Liu, Xi, Xia, Chun-hong, FitzGerald, Paul G., Li, Rachel, Wang, Jessica, Gong, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479064/
https://www.ncbi.nlm.nih.gov/pubmed/32913386