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Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness

Blindness arising from retinal or macular degeneration results in significant social, health and economic burden. While approved treatments exist for neovascular (‘wet’) age-related macular degeneration, new therapeutic targets/interventions are needed for the more prevalent atrophic (‘dry’) form of...

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Detalles Bibliográficos
Autores principales: Sundaramurthi, Husvinee, Roche, Sarah L., Grice, Guinevere L., Moran, Ailis, Dillion, Eugene T., Campiani, Giuseppe, Nathan, James A., Kennedy, Breandán N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479070/
https://www.ncbi.nlm.nih.gov/pubmed/32984302
http://dx.doi.org/10.3389/fcell.2020.00689