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Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness
Blindness arising from retinal or macular degeneration results in significant social, health and economic burden. While approved treatments exist for neovascular (‘wet’) age-related macular degeneration, new therapeutic targets/interventions are needed for the more prevalent atrophic (‘dry’) form of...
Autores principales: | Sundaramurthi, Husvinee, Roche, Sarah L., Grice, Guinevere L., Moran, Ailis, Dillion, Eugene T., Campiani, Giuseppe, Nathan, James A., Kennedy, Breandán N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479070/ https://www.ncbi.nlm.nih.gov/pubmed/32984302 http://dx.doi.org/10.3389/fcell.2020.00689 |
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