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Overcoming anticancer resistance by photodynamic therapy-related efflux pump deactivation and ultrasound-mediated improved drug delivery efficiency

One of the major obstacles to successful chemotherapy is multi-drug resistance (MDR). A multi-drug resistant cancerous cell abnormally overexpresses membrane transporters that pump anticancer drugs out of the cell, resulting in low anticancer drug delivery efficiency. To overcome the limitation, man...

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Detalles Bibliográficos
Autores principales: Kim, Doyeon, Park, Suhyun, Yoo, Hongkeun, Park, Suhyeon, Kim, Jeewon, Yum, Kyuhee, Kim, Kwangmeyung, Kim, Hyuncheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479087/
https://www.ncbi.nlm.nih.gov/pubmed/32897469
http://dx.doi.org/10.1186/s40580-020-00241-8