NLRP3 Sensing of Diverse Inflammatory Stimuli Requires Distinct Structural Features

The NLRP3 inflammasome is central to host defense and implicated in various inflammatory diseases and conditions. While the favored paradigm of NLRP3 inflammasome activation stipulates a unifying signal intermediate that de-represses NLRP3, this view has not been tested. Further, structures within N...

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Detalles Bibliográficos
Autores principales: Rahman, Tabassum, Nagar, Abhinit, Duffy, Ellen B., Okuda, Kendi, Silverman, Neal, Harton, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479093/
https://www.ncbi.nlm.nih.gov/pubmed/32983094
http://dx.doi.org/10.3389/fimmu.2020.01828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479093/
https://www.ncbi.nlm.nih.gov/pubmed/32983094
http://dx.doi.org/10.3389/fimmu.2020.01828

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