IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon

The physiological stresses that diminish tissue stem-cell characteristics remain largely unknown. We previously reported that type I interferon (IFN), which is essential for host antiviral responses, is a physiological stressor for hematopoietic stem cells (HSCs) and small intestinal stem cells (ISC...

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Detalles Bibliográficos
Autores principales: Minamide, Kana, Sato, Taku, Nakanishi, Yusuke, Ohno, Hiroshi, Kato, Tamotsu, Asano, Jumpei, Ohteki, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479133/
https://www.ncbi.nlm.nih.gov/pubmed/32901054
http://dx.doi.org/10.1038/s41598-020-71633-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479133/
https://www.ncbi.nlm.nih.gov/pubmed/32901054
http://dx.doi.org/10.1038/s41598-020-71633-3

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