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The precursor of PI(3,4,5)P(3) alleviates aging by activating daf-18(Pten) and independent of daf-16

Aging is characterized by the loss of homeostasis and the general decline of physiological functions, accompanied by various degenerative diseases and increased rates of mortality. Aging targeting small molecule screens have been performed many times, however, few have focused on endogenous metaboli...

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Detalles Bibliográficos
Autores principales: Shi, Dawei, Xia, Xian, Cui, Aoyuan, Xiong, Zhongxiang, Yan, Yizhen, Luo, Jing, Chen, Guoyu, Zeng, Yingying, Cai, Donghong, Hou, Lei, McDermott, Joseph, Li, Yu, Zhang, Hong, Han, Jing-Dong J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479145/
https://www.ncbi.nlm.nih.gov/pubmed/32901024
http://dx.doi.org/10.1038/s41467-020-18280-4