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The precursor of PI(3,4,5)P(3) alleviates aging by activating daf-18(Pten) and independent of daf-16
Aging is characterized by the loss of homeostasis and the general decline of physiological functions, accompanied by various degenerative diseases and increased rates of mortality. Aging targeting small molecule screens have been performed many times, however, few have focused on endogenous metaboli...
Autores principales: | Shi, Dawei, Xia, Xian, Cui, Aoyuan, Xiong, Zhongxiang, Yan, Yizhen, Luo, Jing, Chen, Guoyu, Zeng, Yingying, Cai, Donghong, Hou, Lei, McDermott, Joseph, Li, Yu, Zhang, Hong, Han, Jing-Dong J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479145/ https://www.ncbi.nlm.nih.gov/pubmed/32901024 http://dx.doi.org/10.1038/s41467-020-18280-4 |
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