Fic Proteins Inhibit the Activity of Topoisomerase IV by AMPylation in Diverse Bacteria

The Fic (filamentation induced by cyclic AMP) domain is a widely distributed motif with a conserved sequence of HPFx[D/E]GN[G/K]R, some of which regulate cellular activity by catalyzing the transfer of the AMP moiety from ATP to protein substrates. Some Fic proteins, including Fic-1 from the soil ba...

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Detalles Bibliográficos
Autores principales: Lu, Can-Hua, McCloskey, Alix, Chen, Fu-Rong, Nakayasu, Ernesto S., Zhang, Li-Qun, Luo, Zhao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479194/
https://www.ncbi.nlm.nih.gov/pubmed/32983060
http://dx.doi.org/10.3389/fmicb.2020.02084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479194/
https://www.ncbi.nlm.nih.gov/pubmed/32983060
http://dx.doi.org/10.3389/fmicb.2020.02084

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