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Fic Proteins Inhibit the Activity of Topoisomerase IV by AMPylation in Diverse Bacteria
The Fic (filamentation induced by cyclic AMP) domain is a widely distributed motif with a conserved sequence of HPFx[D/E]GN[G/K]R, some of which regulate cellular activity by catalyzing the transfer of the AMP moiety from ATP to protein substrates. Some Fic proteins, including Fic-1 from the soil ba...
Autores principales: | Lu, Can-Hua, McCloskey, Alix, Chen, Fu-Rong, Nakayasu, Ernesto S., Zhang, Li-Qun, Luo, Zhao-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479194/ https://www.ncbi.nlm.nih.gov/pubmed/32983060 http://dx.doi.org/10.3389/fmicb.2020.02084 |
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