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Dynamic Hydrogels Based on Double Imine Connections and Application for Delivery of Fluorouracil

Dynamic hydrogels have been prepared by cross-linking of O-carboxymethyl chitosan (O-CMCS) with reversibly connected imino-PEGylated dynamers. The double imine chitosan/dynamer and dynamer bonds and were used to provide tighter structures and adaptive drug release behaviors of the hydrogels. The str...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Pham, Chi-Yen, Yu, Rui, Petit, Eddy, Li, Suming, Barboiu, Mihail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479202/
https://www.ncbi.nlm.nih.gov/pubmed/33005607
http://dx.doi.org/10.3389/fchem.2020.00739