Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography

Lentiviral vectors (LVs) are a popular gene delivery tool in cell and gene therapy and they are a primary tool for ex vivo transduction of T cells for expression of chimeric antigen receptor (CAR) in CAR-T cell therapies. Extensive process and product characterization are required in manufacturing v...

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Detalles Bibliográficos
Autores principales: Transfiguracion, Julia, Tran, Michelle Yen, Lanthier, Stéphane, Tremblay, Sonia, Coulombe, Nathalie, Acchione, Mauro, Kamen, Amine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479275/
https://www.ncbi.nlm.nih.gov/pubmed/32953931
http://dx.doi.org/10.1016/j.omtm.2020.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479275/
https://www.ncbi.nlm.nih.gov/pubmed/32953931
http://dx.doi.org/10.1016/j.omtm.2020.08.005

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