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Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography
Lentiviral vectors (LVs) are a popular gene delivery tool in cell and gene therapy and they are a primary tool for ex vivo transduction of T cells for expression of chimeric antigen receptor (CAR) in CAR-T cell therapies. Extensive process and product characterization are required in manufacturing v...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479275/ https://www.ncbi.nlm.nih.gov/pubmed/32953931 http://dx.doi.org/10.1016/j.omtm.2020.08.005 |