Nuclear deformation mediates liver cell mechanosensing in cirrhosis

BACKGROUND & AIMS: Liver stiffness is increased in advanced chronic liver disease (ACLD) and accurately predicts prognosis in this population. Recent data suggest that extracellular matrix stiffness per se may modulate the phenotype of liver cells. We aimed at investigating the effect of matrix...

Descripción completa

Detalles Bibliográficos
Autores principales: Guixé-Muntet, Sergi, Ortega-Ribera, Martí, Wang, Cong, Selicean, Sonia, Andreu, Ion, Kechagia, Jenny Z., Fondevila, Constantino, Roca-Cusachs, Pere, Dufour, Jean-François, Bosch, Jaime, Berzigotti, Annalisa, Gracia-Sancho, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479345/
https://www.ncbi.nlm.nih.gov/pubmed/32939447
http://dx.doi.org/10.1016/j.jhepr.2020.100145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479345/
https://www.ncbi.nlm.nih.gov/pubmed/32939447
http://dx.doi.org/10.1016/j.jhepr.2020.100145

Ejemplares similares