The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity

Human innate immunity to Trypanosoma brucei involves the trypanosome C-terminal kinesin TbKIFC1, which transports internalized trypanolytic factor apolipoprotein L1 (APOL1) within the parasite. We show that TbKIFC1 preferentially associates with cholesterol-containing membranes and is indispensable...

Descripción completa

Detalles Bibliográficos
Autores principales: Lecordier, Laurence, Uzureau, Sophie, Vanwalleghem, Gilles, Deleu, Magali, Crowet, Jean-Marc, Barry, Paul, Moran, Barry, Voorheis, Paul, Dumitru, Andra-Cristina, Yamaryo-Botté, Yoshiki, Dieu, Marc, Tebabi, Patricia, Vanhollebeke, Benoit, Lins, Laurence, Botté, Cyrille Y., Alsteens, David, Dufrêne, Yves, Pérez-Morga, David, Nolan, Derek P., Pays, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479354/
https://www.ncbi.nlm.nih.gov/pubmed/32889430
http://dx.doi.org/10.1016/j.isci.2020.101476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479354/
https://www.ncbi.nlm.nih.gov/pubmed/32889430
http://dx.doi.org/10.1016/j.isci.2020.101476

Ejemplares similares