Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function

Azithromycin (AZM) has been widely used as an antibacterial drug for many years. It has also been used to treat delayed gastric emptying. However, it exerts several side effects. We found that deglycosylated AZM (Deg-AZM or CP0119), an AZM metabolite, is a positively strong intestinal agonist that m...

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Detalles Bibliográficos
Autores principales: Zhong, Weilong, Sun, Bo, Ruan, Hao, Yang, Guang, Qian, Baoxin, Cao, Hailong, He, Lingfei, Fan, Yunjing, Roberts, Arthur G., Liu, Xiang, Hu, Xuejiao, Liang, Yuan, Ye, Qing, Yin, Tingting, Wang, Bangmao, Yang, Cheng, Sun, Tao, Zhou, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479357/
https://www.ncbi.nlm.nih.gov/pubmed/32889431
http://dx.doi.org/10.1016/j.isci.2020.101464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479357/
https://www.ncbi.nlm.nih.gov/pubmed/32889431
http://dx.doi.org/10.1016/j.isci.2020.101464

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