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An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission

The endosomal sorting complex required for transport-III (ESCRT-III) catalyzes membrane fission from within membrane necks, a process that is essential for many cellular functions, from cell division to lysosome degradation and autophagy. How it breaks membranes, though, remains unknown. Here, we ch...

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Detalles Bibliográficos
Autores principales: Pfitzner, Anna-Katharina, Mercier, Vincent, Jiang, Xiuyun, Moser von Filseck, Joachim, Baum, Buzz, Šarić, Anđela, Roux, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479521/
https://www.ncbi.nlm.nih.gov/pubmed/32814015
http://dx.doi.org/10.1016/j.cell.2020.07.021