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The Brain Microenvironment Induces DNMT1 Suppression and Indolence of Metastatic Cancer Cells

Brain metastasis is an ineffective process, and many cancer cells enter into an indolent state following extravasation in the brain. Single cell RNA sequencing of melanoma brain metastases reveals that non-proliferating brain metastatic melanoma cells exhibit a pattern of gene expression associated...

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Detalles Bibliográficos
Autores principales: Hirata, Eishu, Ishibashi, Kojiro, Kohsaka, Shinji, Shinjo, Keiko, Kojima, Shinya, Kondo, Yutaka, Mano, Hiroyuki, Yano, Seiji, Kiyokawa, Etsuko, Sahai, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479628/
https://www.ncbi.nlm.nih.gov/pubmed/32891059
http://dx.doi.org/10.1016/j.isci.2020.101480