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The Brain Microenvironment Induces DNMT1 Suppression and Indolence of Metastatic Cancer Cells
Brain metastasis is an ineffective process, and many cancer cells enter into an indolent state following extravasation in the brain. Single cell RNA sequencing of melanoma brain metastases reveals that non-proliferating brain metastatic melanoma cells exhibit a pattern of gene expression associated...
Autores principales: | Hirata, Eishu, Ishibashi, Kojiro, Kohsaka, Shinji, Shinjo, Keiko, Kojima, Shinya, Kondo, Yutaka, Mano, Hiroyuki, Yano, Seiji, Kiyokawa, Etsuko, Sahai, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479628/ https://www.ncbi.nlm.nih.gov/pubmed/32891059 http://dx.doi.org/10.1016/j.isci.2020.101480 |
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