Maresin 1 Attenuates Radicular Pain Through the Inhibition of NLRP3 Inflammasome-Induced Pyroptosis via NF-κB Signaling

BACKGROUND: The exposure of the nucleus pulposus (NP) causes an immune and inflammatory response, which is intrinsically linked to the pathogenesis of radicular pain. As a newly discovered pro-resolving lipid mediator, maresin 1 (MaR1) could exert powerful inflammatory resolution, neuroprotection, a...

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Detalles Bibliográficos
Autores principales: Wang, Yi-hao, Li, Yan, Wang, Jun-nan, Zhao, Qing-xiang, Jin, Jin, Wen, Shuang, Wang, Si-cong, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479972/
https://www.ncbi.nlm.nih.gov/pubmed/32982664
http://dx.doi.org/10.3389/fnins.2020.00831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479972/
https://www.ncbi.nlm.nih.gov/pubmed/32982664
http://dx.doi.org/10.3389/fnins.2020.00831

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