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Maresin 1 Attenuates Radicular Pain Through the Inhibition of NLRP3 Inflammasome-Induced Pyroptosis via NF-κB Signaling
BACKGROUND: The exposure of the nucleus pulposus (NP) causes an immune and inflammatory response, which is intrinsically linked to the pathogenesis of radicular pain. As a newly discovered pro-resolving lipid mediator, maresin 1 (MaR1) could exert powerful inflammatory resolution, neuroprotection, a...
Autores principales: | Wang, Yi-hao, Li, Yan, Wang, Jun-nan, Zhao, Qing-xiang, Jin, Jin, Wen, Shuang, Wang, Si-cong, Sun, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479972/ https://www.ncbi.nlm.nih.gov/pubmed/32982664 http://dx.doi.org/10.3389/fnins.2020.00831 |
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