Cofilin Loss in Drosophila Muscles Contributes to Muscle Weakness through Defective Sarcomerogenesis during Muscle Growth

Sarcomeres, the fundamental contractile units of muscles, are conserved structures composed of actin thin filaments and myosin thick filaments. How sarcomeres are formed and maintained is not well understood. Here, we show that knockdown of Drosophila cofilin (DmCFL), an actin depolymerizing factor,...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Mridula, Yu, Shannon F., Chin, Samantha M., Soffar, David B., Windner, Stefanie E., Goode, Bruce L., Baylies, Mary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479987/
https://www.ncbi.nlm.nih.gov/pubmed/32697999
http://dx.doi.org/10.1016/j.celrep.2020.107893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479987/
https://www.ncbi.nlm.nih.gov/pubmed/32697999
http://dx.doi.org/10.1016/j.celrep.2020.107893

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