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Cofilin Loss in Drosophila Muscles Contributes to Muscle Weakness through Defective Sarcomerogenesis during Muscle Growth
Sarcomeres, the fundamental contractile units of muscles, are conserved structures composed of actin thin filaments and myosin thick filaments. How sarcomeres are formed and maintained is not well understood. Here, we show that knockdown of Drosophila cofilin (DmCFL), an actin depolymerizing factor,...
Autores principales: | Balakrishnan, Mridula, Yu, Shannon F., Chin, Samantha M., Soffar, David B., Windner, Stefanie E., Goode, Bruce L., Baylies, Mary K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479987/ https://www.ncbi.nlm.nih.gov/pubmed/32697999 http://dx.doi.org/10.1016/j.celrep.2020.107893 |
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